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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF4B All Species: 17.58
Human Site: S1016 Identified Species: 25.78
UniProt: Q2VIQ3 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2VIQ3 NP_001092763.1 1234 140035 S1016 D T L L S P D S S F E Y I P P
Chimpanzee Pan troglodytes XP_518055 1227 139177 S1009 D T L L S P D S S F E Y I P P
Rhesus Macaque Macaca mulatta XP_001084213 1234 139742 S1016 D T L L S P D S S F E Y V P P
Dog Lupus familis XP_549061 1234 139874 S1018 D T L L S P D S S F E Y I P P
Cat Felis silvestris
Mouse Mus musculus P33174 1231 139533 Q1014 H L T R N I F Q S P D S S F E
Rat Rattus norvegicus Q7M6Z5 1394 158861 S1081 E S I Q N R Q S S L K S S F Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 K997 E N D V L K Q K M L L V Q V A
Frog Xenopus laevis Q91784 1226 138905 L1012 H V A S G K K L H N I L P A A
Zebra Danio Brachydanio rerio Q58G59 1363 154819 A1109 L S A S E T R A L L C K Y F D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 K570 M A Q N E L V K E L K R Q L L
Honey Bee Apis mellifera XP_395595 1064 123475 K846 D R R K Q C I K E S E F M E K
Nematode Worm Caenorhab. elegans P46873 699 78760 Q485 H K D D P L L Q V Y S T T Q E
Sea Urchin Strong. purpuratus P46872 699 78679 L485 I V G G V D L L A K S E E Q E
Poplar Tree Populus trichocarpa XP_002302432 1055 118553 S832 N S L V A M A S Q L S E A E E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_200901 1294 145204 H964 D E N L K N E H S M K K Q E T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 Q714 K A L V D D L Q R R V K A G G
Conservation
Percent
Protein Identity: 100 97.9 90.9 91 N.A. 83.6 26.4 N.A. N.A. 71.3 66.6 25.1 N.A. 27.2 36.8 25.6 27.4
Protein Similarity: 100 98.8 94 94.7 N.A. 90.3 47.2 N.A. N.A. 83.7 80.1 44.1 N.A. 41 55.8 38.5 38.4
P-Site Identity: 100 100 93.3 100 N.A. 6.6 13.3 N.A. N.A. 0 0 0 N.A. 0 13.3 0 0
P-Site Similarity: 100 100 100 100 N.A. 20 46.6 N.A. N.A. 13.3 0 13.3 N.A. 6.6 26.6 6.6 6.6
Percent
Protein Identity: 31.9 N.A. N.A. 30.6 N.A. 26.6
Protein Similarity: 50 N.A. N.A. 49.1 N.A. 44
P-Site Identity: 13.3 N.A. N.A. 20 N.A. 6.6
P-Site Similarity: 40 N.A. N.A. 33.3 N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 13 0 7 0 7 7 7 0 0 0 13 7 13 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % C
% Asp: 38 0 13 7 7 13 25 0 0 0 7 0 0 0 7 % D
% Glu: 13 7 0 0 13 0 7 0 13 0 32 13 7 19 25 % E
% Phe: 0 0 0 0 0 0 7 0 0 25 0 7 0 19 0 % F
% Gly: 0 0 7 7 7 0 0 0 0 0 0 0 0 7 7 % G
% His: 19 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % H
% Ile: 7 0 7 0 0 7 7 0 0 0 7 0 19 0 0 % I
% Lys: 7 7 0 7 7 13 7 19 0 7 19 19 0 0 7 % K
% Leu: 7 7 38 32 7 13 19 13 7 32 7 7 0 7 7 % L
% Met: 7 0 0 0 0 7 0 0 7 7 0 0 7 0 0 % M
% Asn: 7 7 7 7 13 7 0 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 0 7 25 0 0 0 7 0 0 7 25 25 % P
% Gln: 0 0 7 7 7 0 13 19 7 0 0 0 19 13 7 % Q
% Arg: 0 7 7 7 0 7 7 0 7 7 0 7 0 0 0 % R
% Ser: 0 19 0 13 25 0 0 38 44 7 19 13 13 0 0 % S
% Thr: 0 25 7 0 0 7 0 0 0 0 0 7 7 0 7 % T
% Val: 0 13 0 19 7 0 7 0 7 0 7 7 7 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 25 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _